ADC BIO is developing every day. With undiluted focus on a superior process and technology platform to bring the next generation of bio-conjugate therapeutics to life. Rapidly. Innovatively. Cost-effectively. And right first time.
BIO-CONJUGATION SERVICES > DEVELOPMENT
FROM CHEMISTRY.
TO CONJUGATION.
ADC PROTOTYPING TO SUPPORT
PROOF OF CONCEPT.
Prototype Toxin Linkers and ADCs establish proof of concept.
Expert chemistry and conjugation teams allow you to compare and contrast different payloads, different linkers and conjugation strategies for your toxins or antibodies, against clinically validated comparators.
Is time of the essence? We offer a Fast Track Service enabled by:
- Lock-Release and Solution capability.
- Proven experience with most chemical and enzymatic conjugation methodologies.
- Stocks of model antibodies, ADCs, linker building blocks and payloads.
Explore our 4 cornerstones of ADC design and expertise to see how we can help you.
Our experience across the cornerstones of ADC design
PROCESS DEVELOPMENT
TO ENABLE CLINICAL LOT MANUFACTURING.
A ‘right first time’ track record of developing processes and preclinical manufacturing services for your ADCs.
Trust in our process development experts, with their right first time track-record in ADC process development. Integrating chemistry, conjugation and supporting analytics into one team.
- Conjugation chemistry optimisation.
- Development and optimisation of supporting purification techniques.
- Robustness and process characterisation studies.
- QbD process development using DOE and traditional development approaches.
- Milligrams to 10s of gram capability.
SCALE UP AND MANUFACTURE OF
TOXICOLOGY BATCHES
TO support IND enabling preclinical studies
Our development team offers large scale pre-clinical batch manufacture. A reliable and cost-effective way to:
- Demonstrate process transfer or scalability.
- Produce ADCs for pivotal pre-clinical safety studies.
- 10s to 100s of gram capability.
- Working hand in hand with Manufacturing and Quality Control to ensure seamless and successful process transfer and first clinical batches.
